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|Product Name||TRAPPC2, 1-140aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMSGSFYF VIVGHHDNPV FEMEFLPAGK AESKDDHRHL NQFIAHAALD LVDENMWLSN NMYLKTVDKF NEWFVSAFVT AGHMRFIMLH DIRQEDGIKN FFTDVYDLYI KFSMNPFYEP NSPIRSSAFD RKVQFLGKKH LLS|
|Background||TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, this protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in TRAPPC2 are a cause of spondyloepiphyseal dysplasia tarda (SEDT). Recombinant human TRAPPC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||39.7 kDa (351aa)|
|NCBI Accession #||NP_055378|
|Purity||> 90% by SDS-PAGE|
|References||Gécz J, Shaw MA, et al. (2003). Gene. 27;320:137-44.|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Trafficking protein particle complex subunit 2, hYP38334, MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L|
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