| Product Name | TrpM7 Antibody: ATTO 565 |
|---|---|
| Description | TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2). . Mouse Anti-Mouse TrpM7 Monoclonal IgG1 |
| Synonyms | CHAK antibody, CHAK1 antibody, Channel kinase 1 antibody, Channel-kinase 1 antibody, Long transient receptor potential channel 7 antibody, LTrpC-7 antibody, LTRPC7 antibody, Transient receptor potential cation channel subfamily M member 7 antibody, TRP PL |
| Host | Mouse |
| Clone | S74-25 |
| Immunogen | Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7 |
| Isotype | IgG1 |
| Specificity | Detects ~220kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6. |
| Reactivity | Human, Mouse, Rat |
| Applications | AM, ICC, IF, IHC, WB |
| Form | Purified, in PBS pH7.4, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_001157797.1. 58800 |
| Uniprot | Q923J1 |
| Supplier | Stressmarq Biosciences |
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