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|Product Name||VAPA, 1-227aa, Human|
|Background||VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein is a SNARE regulator with high levels of expression in the intestine during late embryogenesis and early neonatal development. VAPA may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Recombinant VAPA protein was expressed in E.coli and purified by using conventional chromatography techniques.|
|Synonyms||hVAP-33, VAP-33, VAP-A, VAP33, Vesicle-associated membrane protein-associated protein A VAMP A, VAMP associated protein A, VAP 33, VAP A, Vesicle associated membrane protein associated protein A.|
|AA Sequence||MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAS ASGAMAKHEQ ILVLDPPTDL KFKGPFTDVV TTNLKLRNPS DRKVCFKVKT TAPRRYCVRP NSGIIDPGST VTVSVMLQPF DYDPNEKSKH KFMVQTIFAP PNTSDMEAVW KEAKPDELMD SKLRCVFEMP NENDKLNDME PSKAVPLNAS KQDGPMPKPH SVSLNDTETR KLMEECKRLQ GEMMKLSEEN RHLRDEGLRL RKVAHSDKPG STSTASFRDN VTSP|
|Molecular Weight||23.9 kDa (210aa), confirmed by MALDI-TOF.|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Purity||> 85% by SDS-PAGE|
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Intended Use||For Research Use Only|
|References||Wyles JP., et al. (2002) J Biol Chem. 277(33):29908-18.
Weir ML., et al. (2001) Biochem Biophys Res Commun. 286(3):616-21.
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