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|Product Name||VPS29 1-182aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSHMMLVLV LGDLHIPHRC NSLPAKFKKL LVPGKIQHIL CTGNLCTKES YDYLKTLAGD VHIVRGDFDE NLNYPEQKVV TVGQFKIGLI HGHQVIPWGD MASLALLQRQ FDVDILISGH THKFEAFEHE NKFYINPGSA TGAYNALETN IIPSFVLMDI QASTVVTYVY QLIGDDVKVE RIEYKKP|
|Background||Vacuolar protein sorting 29, also known as VPS29, belongs to a group of genes coding for vacuolar protein sorting (VPS) proteins that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. It is a late Golgi transmembrane protein that acts as the sorting receptor for soluble vacuolar hydrolases, from the prevacuolar endosome back to the Golgi. Also, VPS29 may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Recombinant human VPS29 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.|
|Concentration||1mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol|
|Intended Use||For Research Use Only|
|Molecular Weight||37.8kDa (339aa)|
|NCBI Accession #||NP_057310|
|Purity||> 90% by SDS-PAGE|
|References||Verges M., et al. (2004) Nat. Cell Biol. 6:763-769
Damen E., et al. (2006) Biochem. J. 398:399-409
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Vacuolar protein sorting-associated protein, DC15, DC7, PEP11|
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