ABCB11 Antibody

Category: Antibodies
Catalog
CSB-PA447968
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Product Name ABCB11 Antibody
Description Rabbit polyclonal antibody to ABCB11
Synonyms ABC member 16; MDR/TAP subfamily antibody; ABC16 antibody; ABCB1 antibody; Abcb11 antibody; ABCBB_HUMAN antibody; ATP binding cassette sub family B (MDR/TAP) member 11 antibody; ATP binding cassette sub family B member 11 antibody; ATP-binding cassette sub-family B member 11 antibody; Bile salt export pump antibody; BRIC2 antibody; Bsep antibody; PFIC 2 antibody; PFIC2 antibody; PGY4 antibody; progressive familial intrahepatic cholestasis 2 antibody; Sister of P glycoprotein antibody; Spgp antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthetic peptide of human ABCB11
Isotype IgG
Target ABCB11
Reactivity Human, Mouse, Rat
Applications ELISA, IHC
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot O95342
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Supplier Cusabio

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