| Product Name | ACVR2A, 20-135aa, Human, Baculovirus |
|---|---|
| Description | ACVR2A, also known as activin receptor type-2A, is involved in a wide range of biological processes including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis, the regulation of reproductive physiology, inflammation, and carcinogenesis. They function through heteromeric complexes of type I and type II serine/threonine kinase receptors. Recombinant human ACVR2A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Synonyms | Activin receptor type-2A, ACVR2A, ACTRII, ACVR2 |
| Host | Virus |
| Molecular Weight |
60.9kDa (563aa) 50-70kDa (SDS-PAGE under reducing conditions) |
| Amino Acid Sequence | AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPPLEHH HHHH |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
| Concentration | 0.5mg/ml (determined by Absorbance at 280nm) |
| Purity | > 95% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Welt C., et al. (2002) Exp Biol Med. 227:724-752. Chen YG., et al. (2006) Exp Biol Med. 231:534-544. |
| Background | ACVR2A, also known as activin receptor type-2A, is involved in a wide range of biological processes including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis, the regulation of reproductive physiology, inflammation, and carcinogenesis. They function through heteromeric complexes of type I and type II serine/threonine kinase receptors. Recombinant human ACVR2A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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