| Product Name | ADIPOQ Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to Adiponectin |
| Synonyms | 30 kDa adipocyte complement-related protein |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1A1B3 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Adiponectin |
| Isotype | IgG2b |
| Target | ADIPOQ |
| Specificity | specific for human Adiponectin denatured and native forms |
| Reactivity | Human |
| Applications | ELISA |
| Form | liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q15848 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
| Supplier | Cusabio |
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