Product Name | ADRA1A Polyclonal Antibody |
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Description | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. |
Synonyms | ADRA1C,ADRA1L1,ALPHA1AAR |
Host | Rabbit |
Immunogen | Synthetic peptide of human ADRA1A |
Isotype | IgG |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IHC, WB |
Form | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Uniprot | P35348 |
Background | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. |
Supplier | Elabscience |
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