Product Name | ADRA2A Antibody |
---|---|
Description | Rabbit polyclonal antibody to alpha 2a Adrenergic Receptor |
Synonyms | ADA2A_HUMAN antibody; ADRA2 antibody; ADRA2A antibody; ADRA2R antibody; ADRAR antibody; Adrenergic alpha 2A receptor antibody; Alpha 2 adrenergic receptor subtype C10 antibody; Alpha 2A adrenergic receptor antibody; Alpha 2AAR subtype C10 antibody; Alpha-2 adrenergic receptor subtype C10 antibody; alpha-2-adrenergic receptor; platelet type antibody; Alpha-2A adrenergic receptor antibody; Alpha-2A adrenoceptor antibody; Alpha-2A adrenoreceptor antibody; Alpha-2AAR antibody; ALPHA2AAR antibody; OTTHUMP00000058849 antibody; ZNF32 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthesized peptide derived from internal of human Adrenergic Receptor _-2A. |
Isotype | IgG |
Target | ADRA2A |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, IF, IHC, WB |
Form | liquid |
Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Uniprot | P08913 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background |
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. Kobilka B.K., Science 238:650-656(1987). Fraser C.M., J. Biol. Chem. 264:11754-11761(1989). Guyer C.A., J. Biol. Chem. 265:17307-17317(1990). |
Supplier | Cusabio |
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