Product Name | AGBL4 Antibody |
---|---|
Description | Rabbit polyclonal antibody to AGBL4 |
Synonyms | AGBL4 antibody; ATP/GTP binding protein like 4 antibody; ATP/GTP-binding protein-like 4 antibody; CBPC6_HUMAN antibody; CCP6 antibody; Cytosolic carboxypeptidase 6 antibody; FLJ14442 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthesized peptide derived from internal of human CBCP6. |
Isotype | IgG |
Target | AGBL4 |
Reactivity | Human |
Applications | ELISA, WB |
Form | liquid |
Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Uniprot | Q5VU57 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background |
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity. Ota T., Nat. Genet. 36:40-45(2004). Gregory S.G., Nature 441:315-321(2006). |
Supplier | Cusabio |
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