| Product Name | AGRN Polyclonal Antibody |
|---|---|
| Description | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. |
| Host | Rabbit |
| Immunogen | Synthetic peptide of human AGRN |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | O00468 |
| Background | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. |
| Supplier | Elabscience |
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