| Product Name | Ah Receptor Polyclonal Antibody |
|---|---|
| Description | The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.AHR (Aryl Hydrocarbon Receptor) is a Protein Coding gene. Diseases associated with AHR include Eosinophilic Fasciitis and Seborrheic Dermatitis. Among its related pathways are Cytochrome P450 - arranged by substrate type and Circadian rythm related genes. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is ENSG00000283321. |
| Synonyms | AHR, BHLHE76, Aryl hydrocarbon receptor, Ah receptor, AhR, Class E basic helix-loop-helix protein 76, bHLHe76, AHRR, BHLHE77, KIAA1234, Aryl hydrocarbon receptor repressor, AhR repressor, AhRR, Class E basic helix-loop-helix protein 77, bHL |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from human Ah Receptor around the non-phosphorylation site of Ser36. |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P35869/A9YTQ3 |
| Background | The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.AHR (Aryl Hydrocarbon Receptor) is a Protein Coding gene. Diseases associated with AHR include Eosinophilic Fasciitis and Seborrheic Dermatitis. Among its related pathways are Cytochrome P450 - arranged by substrate type and Circadian rythm related genes. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is ENSG00000283321. |
| Supplier | Elabscience |
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