| Product Name | AHA-1 Polyclonal Antibody |
|---|---|
| Description | AHSA1 (Activator Of HSP90 ATPase Activity 1) is a Protein Coding gene. Diseases associated with AHSA1 include Stomatitis and Hypoparathyroidism-Deafness-Renal Disease Syndrome. Among its related pathways are Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) and T cell receptor signaling pathway. GO annotations related to this gene include chaperone binding and ATPase activator activity. An important paralog of this gene is AHSA2.Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. |
| Synonyms | AHSA1; C14orf3; HSPC322; Activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; p38 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the Internal region of human AHA-1 |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | O95433 |
| Background | AHSA1 (Activator Of HSP90 ATPase Activity 1) is a Protein Coding gene. Diseases associated with AHSA1 include Stomatitis and Hypoparathyroidism-Deafness-Renal Disease Syndrome. Among its related pathways are Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF) and T cell receptor signaling pathway. GO annotations related to this gene include chaperone binding and ATPase activator activity. An important paralog of this gene is AHSA2.Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. |
| Supplier | Elabscience |
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