| Product Name | AHA1 Antibody |
|---|---|
| Description | Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4). Mouse Anti-Human AHA1 Monoclonal IgG1 Kappa |
| Synonyms | Aha 1 Antibody, Ahsa1 Antibody, p38 Antibody, HSPC322 Antibody, C14orf3 Antibody, Activator of HSP90 ATPase Antibody, Activator of 90 kDa heat shock protein ATPase homolog 1 Antibody |
| Host | Mouse |
| Clone | 4H9-D7 |
| Immunogen | Human Aha1, his tagged |
| Isotype | IgG1 kappa |
| Specificity | Detects ~38kDa, can run up to 45kDa on SDS Page. It sees human Aha1, Mouse Aha1 and Mouse Aha2. |
| Reactivity | Human, Mouse |
| Applications | ELISA, ICC, IF, WB |
| Form | Purified, in PBS pH7.2, 50% glycerol, 0.09% sodium azide |
| Gene Id | NP_036243.1. 10598 |
| Uniprot | O95433 |
| Background | Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4). |
| Supplier | Stressmarq Biosciences |
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