| Product Name | AKAP 10 Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death.AKAP10 (A-Kinase Anchoring Protein 10) is a Protein Coding gene. Diseases associated with AKAP10 include Cardiac Conduction Defect and Sudden Cardiac Death. Among its related pathways are Activation of cAMP-Dependent PKA and Factors involved in megakaryocyte development and platelet production. |
| Synonyms | AKAP10; A-kinase anchor protein 10; mitochondrial; AKAP-10; Dual specificity A kinase-anchoring protein 2; D-AKAP-2; Protein kinase A-anchoring protein 10; PRKA10 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the N-terminal region of human AKAP 10 |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | O43572 |
| Background | This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death.AKAP10 (A-Kinase Anchoring Protein 10) is a Protein Coding gene. Diseases associated with AKAP10 include Cardiac Conduction Defect and Sudden Cardiac Death. Among its related pathways are Activation of cAMP-Dependent PKA and Factors involved in megakaryocyte development and platelet production. |
| Supplier | Elabscience |
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