| Product Name | Akt substrate |
|---|---|
| Description | Akt substrate peptide, also known as Akt/SKG substrate peptide, is a 7 amino acid synthetic peptide suitable as a substrate for Akt, also known as protein kinase B (PKB), the serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration. Unlike other substrates, Akt substrate peptide is not phosphorylated by p70 S6 kinase or MAP kinase activated protein (MAPKAP) kinase-1. |
| Synonyms | Akt/SKG substrate peptide |
| Molecular Weight | 817.9 Da |
| Target | Kinases |
| Amino Acid Sequence | RPRAATF |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Cas Number | 276680-69-4 |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: None |
| References |
Alessi et al (1996) Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399 333 PMID: 8985174 Cutillas et al (2006) Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase / Akt signal transduction pathway by mass spectrometry. Proc.Natl.Acad.Sci.U.S.A. 103 8959 PMID: 16751276 Related areasAll kinase modulators >All substrate peptides > |
| Supplier | Isca Biochemicals Limited |
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