| Product Name | ALDH1A1 Monoclonal Antibody |
|---|---|
| Description | ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ),also named as ALDC,ALDH1 and PUMB1,belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase,an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells. And it is important for multiple biological activities including drug resistance,cell differentiation,and oxidative stress response. As a novel cancer stem cell marker,ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast,lung,ovarian or colon cancer. |
| Synonyms | ALDC,ALDH E1,ALDH1,ALDH11,ALDH1A1,ALHDII,PUMB1,RALDH 1,RALDH1,Retinal dehydrogenase 1 |
| Host | Mouse |
| Clone | 395 |
| Immunogen | Fusion protein of ALDH1A1 |
| Isotype | IgG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.1% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P00352 |
| Background | ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ),also named as ALDC,ALDH1 and PUMB1,belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase,an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells. And it is important for multiple biological activities including drug resistance,cell differentiation,and oxidative stress response. As a novel cancer stem cell marker,ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1A1 in relatively restricted or limited levels such as breast,lung,ovarian or colon cancer. |
| Supplier | Elabscience |
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