Product Name | ALOX15B Antibody |
---|---|
Description | Rabbit polyclonal antibody to ALOX15B |
Synonyms | 15 Lipoxygenase 2 antibody; 15 LO 2 antibody; 15 LOX 2 antibody; 15-lipoxygenase 2 antibody; 15-LOX-2 antibody; 15-LOX-B antibody; Alox15b antibody; Arachidonate 15 lipoxygenase second type antibody; Arachidonate 15 lipoxygenase type II antibody; Arachidonate 15-lipoxygenase B antibody; Arachidonate 15-lipoxygenase type II antibody; LX15B_HUMAN antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Recombinant human Arachidonate 15-lipoxygenase B protein (1-200AA) |
Isotype | IgG |
Target | ALOX15B |
Reactivity | Human |
Applications | ELISA, IHC, WB |
Form | Liquid |
Diluent Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Uniprot | O15296 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells. |
Supplier | Cusabio |
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