alpha-Synuclein A53T, Human, Recombinant

Proteins, Recombinant
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Product Name alpha-Synuclein A53T, Human, Recombinant
Applications SDS-PAGE
Background A Parkinson's disease-related point mutant (A53T) of alpha-synuclein. A53T mutant of alpha-synuclein was overexpressed in E. coli and the recombinant protein was purified to apparent homogeneity by taking advantage of the thermosolubility of the protein and by using conventional column chromatography techniques
Concentration 1 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris pH 7.5
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 21 kDa (196 aa), confirmed by MALDI-TOF.
NCBI Accession # NP_000336.1
Purity > 95% by SDS-PAGE
References Polymeropoulos MH., et al. (1997) Science. 276, 2045-7.
Park, SM. et al. (2002) Blood. 100(7),2506-2514
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms SNCA, NACP, PARK1, alpha-Synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Alpha synuclein, Alpha-synuclein isoform NACP140, alphaSYN, MGC105443, MGC110988, MGC127560, MGC64356, Non A beta component of AD amyloid, Non A4 component of amyloid precursor, Non-A-beta component of alzheimers disease amyloid, precursor of PARK 1, PARK 4, PARK4, Parkinson disease familial 1, PD 1, PD1, Synuclein alpha,
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