Product Name | AMZ2 Antibody |
---|---|
Description | Rabbit polyclonal antibody to AMZ2 |
Synonyms | AMZ2 antibody; AMZ2_HUMAN antibody; Archaelysin family metallopeptidase 2 antibody; Archaemetzincin 2 antibody; Archaemetzincin-2 antibody; Archeobacterial metalloproteinase like protein 2 antibody; Archeobacterial metalloproteinase-like protein 2 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human AMZ2 |
Isotype | IgG |
Target | AMZ2 |
Reactivity | Human |
Applications | ELISA, IHC |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q86W34 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin. |
Supplier | Cusabio |
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