ANAPC10 Polyclonal Antibody

Category: Antibodies
Catalog
E-AB-14578
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Product Name ANAPC10 Polyclonal Antibody
Description ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940)
Synonyms DOC1,APC10
Host Rabbit
Immunogen Recombinant protein of human ANAPC10
Isotype IgG
Reactivity Human, Mouse
Applications ELISA, IHC
Form PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Uniprot Q9UM13
Background ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940)
Supplier Elabscience

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