ANGPT2 Antibody, HRP conjugated

Category: Antibodies
Catalog
CSB-PA05749B0Rb
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Product Name ANGPT2 Antibody, HRP conjugated
Description Rabbit polyclonal antibody against Angiopoietin 2 conjugated to HRP
Synonyms AGPT 2 antibody; Agpt2 antibody; ANG 2 antibody; ANG-2 antibody; ANG2 antibody; Angiopoietin 2a antibody; Angiopoietin 2B antibody; Angiopoietin-2 antibody; Angiopoietin2 antibody; ANGP2_HUMAN antibody; ANGPT 2 antibody; Angpt2 antibody; Tie2 ligand antibody
Host Rabbit
Clonality Polyclonal
Conjugate HRP
Immunogen Recombinant human Angiopoietin-2 protein (19-485AA)
Isotype IgG
Target ANGPT2
Reactivity Human
Applications ELISA
Form Liquid
Diluent Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Uniprot O15123
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Supplier Cusabio

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