| Product Name | ANGPTL3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ANGPTL3 |
| Synonyms | Angiopoietin-related protein 3, FHBL2, ANGPT5 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein corresponding to C terminal 300 amino acids of Human Angiopoietin-related protein 3 |
| Isotype | IgG |
| Target | ANGPTL3 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | liquid |
| Diluent Buffer | Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. |
| Uniprot | Q9Y5C1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. |
| Supplier | Cusabio |
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