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|Product Name||ANKRD1, 1-319aa, Human|
|Amino Acid Sequence||MGSSHHHHHH SSGLVPRGSH MGSMMVLKVE ELVTGKKNGN GEAGEFLPED FRDGEYEAAV TLEKQEDLKT LLAHPVTLGE QQWKSEKQRE AELKKKKLEQ RSKLENLEDL EIIIQLKKRK KYRKTKVPVV KEPEPEIITE PVDVPTFLKA ALENKLPVVE KFLSDKNNPD VCDEYKRTAL HRACLEGHLA IVEKLMEAGA QIEFRDMLES TAIHWASRGG NLDVLKLLLN KGAKISARDK LLSTALHVAV RTGHYECAEH LIACEADLNA KDREGDTPLH DAVRLNRYKM IRLLIMYGAD LNIKNCAGKT PMDLVLHWQN GTKAIFDSLR ENSYKTSRIA TF|
|Background||Ankyrin repeat domain-containing protein 1, also known as ANKRD1, may play an important role in endothelial cell activation. This protein may act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Recombinant human ANKRD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|Form||Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol,1mM DTT|
|Intended Use||For Research Use Only|
|Molecular Weight||21 kDa (187aa) confirmed by MALDI-TOF|
|NCBI Accession #||NP_055206|
|Purity||> 85% by SDS-PAGE|
|References||Chu W., et al. (1995) J. Biol. Chem. J. Biol. Chem. 270:10236-10245
Park J.-H., et al. (2005) Cancer Res. 65:2804-2814
|Storage||Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.|
|Synonyms||Ankyrin repeat domain-containing protein 1, ALRP, bA320F15.2, C-193, CARP, CVARP, MCARP|
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