Product Name | ANPRA Rabbit Polyclonal Antibody |
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Description | natriuretic peptide receptor 1(NPR1) Homo sapiens Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (A |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Synthesized peptide derived from part region of human protein |
Isotype | IgG |
Molecular Weight | 116 |
Reactivity | Human, Mouse, Rat |
Applications | ELISA, WB |
Diluent Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
Concentration | 1 mg/ml |
Storage | Store at -20°C. Avoid repeated freeze-thaw cycles. |
Supplier | ELK Biotechnology |
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