| Product Name | Anti-2B4 Antibody [2B4.69] |
|---|---|
| Description | Mouse monoclonal [2B4.69] antibody to 2B4. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2B4.69 |
| Conjugate | Unconjugated |
| Immunogen | CD244 Fusion protein. |
| Isotype | IgG1 |
| Target | 2B4 |
| Specificity | This antibody recognises the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4). CD244 is a 370 amino acid single pass type I transmembrane glycoprotein with two Ig-like V type domains. CD244 is a member of the SLAM family of receptors expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.CD244 was originally identified as an activating receptor on NK cells, The receptor may have a wide range of activities including NK cell activation, co-stimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of CD244 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family. |
| Reactivity | Human |
| Applications | FC, IP |
| Working Dilutions | Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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