anti-AAV VP1/VP2/VP3 mouse monoclonal, B1, liquid, purified
| Product Name | anti-AAV VP1/VP2/VP3 mouse monoclonal, B1, liquid, purified |
|---|---|
| Description | The B1 antibody reacts with free VP1, VP2 and VP3 of adeno-associated virus (AAV) and at a reduced degree with assembled viral particles. VP1 and VP2 are highly enriched in the nucleus, while non-assembled VP3 is evenly distributed in the nucleus and the cytoplasm. Epitope mapping experiments (Wobus et al., 2000) identified aa726 to aa733 (C-terminus; common to all 3 VP proteins) as the specific binding region. The antibody is also useful for characterization of different stages of infection.Wobus, C. E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281-93 (2000). Limited Use Label License: Research Use OnlyProduct is exclusively licensed to PROGEN Biotechnik GmbH. The use of these products for the development, manufacturing and sale of secondary products/derivatives which are based on the purchased products and/or which include the purchased product require a royalty based sub-license agreement. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | B1 |
| Conjugate | Unconjugated |
| Immunogen | AAV2 capsids |
| Isotype | IgG1 |
| Target | AAV6,AAV1,AAV9,AAV5,AAV8,AAV7,AAV3,AAVrh10,AAV2,AAVDJ |
| Applications | DOT, ICC, IF, IP, WB, IAC |
| Form | PBS, pH 7.4 with 0.09% sodium azide and 0.5% BSA |
| Concentration | 50 µg/ml |
| Storage | Up to 1 month: 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles |
| Supplier | Progen |
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