Anti-ACAT1 (clone AT15E5)

Antibodies, Monoclonal Antibodies
Questions? Contact Us
More Information
Product Name Anti-ACAT1 (clone AT15E5)
Description ACAT1 (acetyl-Coenzyme A acetyltransferase 1) is a 417 amino acid protein. ACAT1 is a mitochondrial enzyme involved in the formation and degradation of ketone bodies and is necessary for the proper metabolic processing of isoleucine. ACAT1 and ACAT2 catalyze the formation of acetoacetyl-CoA from two acetyl-CoA molecules. These enzymes are also capable of the reverse reaction. Defects in ACAT1 are a cause of 3-ketothiolase deficiency. 3-ketothiolase deficiency is an inborn error of isoleucine catabolism characterized by intermittent ketoacidotic attacks associated with unconsciousness. Some patients die during an attack or are mentally retarded.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone AT15E5. Anti-human ACAT1 mAb, clone AT2C5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACAT1 protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.01% Sodium Azide.
Species Mouse
Host Mouse
Isotype IgG1, K
Immunogen Recombinant human ACAT1 (34-427aa) purified from E. coli
Interest Fields Metabolism
NCBI Number NP_000010
References Antonenkov, V.D., et al. (2000) Eur J Biochem 267: 2981-2990Korman, S.H. (2006) Mol Genet Metab 89: 289-299Yamaguchi, S., et al. (1988) J Clin Invest 81(3): 813€“817
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms Acetyl-CoA acetyltransferase 1, ACAT, MAT, T2, THIL
Working Dilutions Optimal dilution should be performed by user.

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.

Customers Also Viewed
  1. Anti-CHUK Polyclonal Antibody
    Anti-CHUK Polyclonal Anti...
    IF, IHC, IP, WB
  2. sFRP-1, Human, Recombinant
    sFRP-1, Human, Recombinan...
    Secreted Frizzled Re...

Hi, have questions?

An ARP Customer Service Representative is happy to help!

or Call (800) 832-2611