| Product Name | Anti-ACE2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ACE2. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to a region within the N terminus of human ACE2. |
| Isotype | IgG |
| Target | ACE2 |
| Specificity | This antibody recognises human Angiotensin-converting enzyme 2, also known as ACE2, ACE-related carboxypeptidase or Metalloprotease MPROT15. ACE2 is a 788 amino acid ~100 kDa carboxypeptidase expressed in a range of tissues including heart, kidney, testis and the gastrointestinal system. ACE2 is a homologue of ACE (Angiotensin-converting enzyme 1), although it has a distinct catalytic activity. ACE2 catalyzes the cleavage of active angiotensin II into angiotensin 1-7, which may counteract the effects of ACE by increasing vasodilatation.ACE2 serves as the cellular entry point for the severe acute respiratory syndrome (SARS) virus, functioning as a receptor for the SARS Spike protein. |
| Reactivity | Human |
| Applications | IHC-P, WB |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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