| Product Name | Anti-Adipophilin Antibody [ADFP/1494] |
|---|---|
| Description | Mouse monoclonal [ADFP/1494] antibody to Adipophilin. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ADFP/1494 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 249-376, of human Adipophilin protein. The exact sequence is proprietary. |
| Isotype | IgG2b |
| Molecular Weight | 48 kDa |
| Target | Adipophilin |
| Specificity | This antibody recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. |
| Reactivity | Human |
| Applications | ELISA, IHC-P |
| Working Dilutions | IHC-P: 2-4 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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