| Product Name | Anti-Aggrecan Antibody [7E1] |
|---|---|
| Description | Mouse monoclonal [7E1] antibody to Aggrecan. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7E1 |
| Conjugate | Unconjugated |
| Immunogen | Purified human articular cartilage aggrecan. |
| Isotype | IgG1 |
| Target | Aggrecan |
| Specificity | This antibody recognises human aggrecan, a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS).A panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. There is a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues. recognises a ~205 kDa trypsin derived fragment of aggrecan.Note: Originally described as being of the isotype IgM, clone 7E1 was found to be unstable and was re-cloned by the originator and the new stable sub-clone was confirmed as being an IgG1. |
| Reactivity | Bovine, Human |
| Applications | IHC-Fr, ELISA, ICC, IP, WB |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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