| Product Name | Anti-AKT1 Antibody [AKT1/3898R] - BSA and Azide free |
|---|---|
| Description | Recombinant rabbit monoclonal [AKT1/3898R] antibody to AKT1. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | AKT1/3898R |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 85-189, of human AKT1 protein. The exact sequence is proprietary. |
| Isotype | IgG |
| Molecular Weight | 62 kDa |
| Target | AKT1 |
| Specificity | This antibody recognizes a protein of 62kDa, which is identified as AKT1The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1(IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Working Dilutions | WB: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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