Anti-AKT1 Monoclonal Antibody

Category: Antibodies
Catalog
152617
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Product Name Anti-AKT1 Monoclonal Antibody
Description The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival.
Host Mouse
Clone V7
Immunogen Ovalbumin-conjugated synthetic peptide KDPMQRLGGG (C-terminal sequence)
Isotype IgG2a Kappa
Reactivity Zebrafish
Applications ELISA, IHC, WB
Supplier Vertebrate Antibodies Limited

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