Anti-AKT1 (phospho Tyr315) + AKT2 (phospho Tyr316) + AKT3 (phospho Tyr312) Antibody
| Product Name | Anti-AKT1 (phospho Tyr315) + AKT2 (phospho Tyr316) + AKT3 (phospho Tyr312) Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to AKT1 (phospho Tyr315) + AKT2 (phospho Tyr316) + AKT3 (phospho Tyr312). |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Phospho-specific peptide corresponding to residues surrounding Tyr315 of human AKT1/ Tyr316 of human AKT2/ Tyr312 of human AKT3. |
| Isotype | IgG |
| Target | AKT1 phospho Tyr315 + AKT2 phospho Tyr316 + AKT3 phospho Tyr312 |
| Specificity | This antibody recognises AKT1 when phosphorylated at tyrosine 315, AKT2 when phosphorylated at tyrosine 316 and AKT3 when phosphorylated at tyrosine 312. AKT 1, 2 and 3 are serine/threonine protein kinases that play a key role in the PI3K-Akt signaling pathway, known to regulate cell growth, proliferation and survival. AKT1 is phosphorylated at tyrosine 315 (corresponding to tyrosine 316/312 of AKT2/AKT3 respectively) by Src and PTK6, tyrosine phosphorylation is important for growth factor mediated activation of AKT. |
| Reactivity | Human, Mouse |
| Applications | WB |
| Working Dilutions | WB: 1:500 - 1:1,000 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol. |
| Concentration | Lot Specific |
| Storage | Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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