Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [ALPL/597]
| Product Name | Anti-Alkaline Phosphatase, Tissue Non-Specific Antibody [ALPL/597] |
|---|---|
| Description | Mouse monoclonal [ALPL/597] antibody to Alkaline Phosphatase, Tissue Non-Specific. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ALPL/597 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human ALPL protein. |
| Isotype | IgG1 |
| Molecular Weight | 55 kDa |
| Target | Alkaline Phosphatase, Tissue Non-Specific |
| Specificity | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. |
| Reactivity | Bovine, Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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