| Product Name | Anti-Angiotensin I Antibody [Ang E9 (BGN/KA/4H)] |
|---|---|
| Description | Mouse monoclonal [Ang E9 (BGN/KA/4H)] antibody to Angiotensin I. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Ang E9 (BGN/KA/4H) |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide sequence PFHLVIHNES(C) corresponding to amino acids 40-49 of the angiotensinogen precursor conjugated to HMW carrier protein. |
| Isotype | IgG2a |
| Target | Angiotensin I |
| Amino Acid Sequence | PFHLVIHNES(C) |
| Protein Length | 10 |
| Specificity | This antibody recognises Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA. Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body. Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure. |
| Reactivity | Human |
| Applications | ELISA |
| Working Dilutions | In a simple indirect ELISA, using 1 µg of Angiotensin I coated per well, the 50% binding was observed at an antibody dilution of 1:12K. Under the same conditions, the end point titre was observed at an antibody dilution of 1:100K. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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