Anti-Apolipoprotein B Antibody [APOB/4332] - BSA and Azide free
| Product Name | Anti-Apolipoprotein B Antibody [APOB/4332] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [APOB/4332] antibody to Apolipoprotein B. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | APOB/4332 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 592-689, of human Apolipoprotein B. The exact sequence is proprietary. |
| Isotype | IgG1 |
| Molecular Weight | 512 kDa |
| Target | Apolipoprotein B |
| Specificity | Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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