| Product Name | Anti-ARID1A Antibody [ARID1A/7735] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [ARID1A/7735] antibody to ARID1A. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ARID1A/7735 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment (around Amino Acids 1900-2000) of human ARID1A protein. The exact sequence is proprietary. |
| Isotype | IgG2b |
| Molecular Weight | 165-320 kDa |
| Target | ARID1A |
| Specificity | The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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