| Product Name | Anti-ATF2 Antibody [PCRP-ATF2-1B4] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [PCRP-ATF2-1B4] antibody to ATF2. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PCRP-ATF2-1B4 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human ATF2 protein. |
| Isotype | IgG2b |
| Molecular Weight | 54.5 kDa |
| Target | ATF2 |
| Specificity | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene. |
| Reactivity | Human |
| Applications | FC, IF, IP, WB |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IP: 1-2µg / 100-500µg proteins, WB: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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