| Product Name | Anti-ATG12 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ATG12. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to 15 amino acids near the centre of human ATG12. |
| Isotype | IgG |
| Molecular Weight | Approximately 40 kDa in mouse heart tissue lysate. |
| Target | ATG12 |
| Protein Length | 15 |
| Specificity | This antibody recognises human Autophagy-related protein 12 (ATG12). ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.There are at least two isoforms of ATG12. |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC-P, WB |
| Working Dilutions | IHC-P: 2.5 µg/ml, WB: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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