| Product Name | Anti-ATG16L1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ATG16L1. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to 18 amino acids from near the centre of human ATG16. |
| Isotype | IgG |
| Molecular Weight | Approximately 75 kDa in HeLa cell lysate. |
| Target | ATG16L1 |
| Protein Length | 18 |
| Specificity | This antibody recognises human Autophagy-related protein 16 (ATG16). ATG16 is a member of the autophagy protein family and forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions.Multiple isoforms of ATG16 exist. |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC-Fr, WB |
| Working Dilutions | WB: 0.25 - 0.5 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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