| Product Name | Anti-ATG5 Antibody [ATG5/2101] |
|---|---|
| Description | Mouse monoclonal [ATG5/2101] antibody to ATG5. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ATG5/2101 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 1-119, of human ATG5 protein. The exact sequence is proprietary. |
| Isotype | IgG1 |
| Molecular Weight | 50-32 kDa |
| Target | ATG5 |
| Specificity | The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy; a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful. |
| Reactivity | Human |
| Applications | ELISA, IHC-P, WB |
| Working Dilutions | ELISA: 1-5 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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