| Product Name | Anti-Axin1 (AT1A4) |
|---|---|
| Description | Axin was originally identified as the product of the mouse gene called fused or fu (renamed Axin), and has since been shown to play a crucial role in controlling axis formation during embryonic development. Axin1 is characterized to be a tumor suppressor and numerous gene mutations have been identified throughout Axin1 from a number of different cancers. Axin can identify in a mouse mutant strain, created by random integration of a transgene. Also, Axin1 plays an important role in the formation of the embryonic neural axis. Recently, it was reported that Axin is found in mitotic spindles and centrosomes. |
| Synonyms | AXIN, Axin-1, Axis inhibition protein 1, hAxin, MGC52315, axin 1 |
| Host | Mouse |
| Clone | AT1A4. Anti-human Axin1 mAb, clone AT1A4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Axin1 protein. |
| Immunogen | Recombinant human Axin1 (546-752aa) purified from E. coli |
| Isotype | K,IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IP, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Kim S M, et al. (2009) Exp. Cell Res. 315: 943-954 Hsiao-Man Ivy Yu, et al. (2007) Mech Dev, 124(2): 146-156. Liu W, et al. (2006) EMBO J, 25(8):1646-58. Salahshor S, et al. (2005) J Clin Pathol, 58(3):225-36. |
| Supplier | ARP |
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