| Product Name | Anti-Basic Cytokeratin Antibody [SPM591] |
|---|---|
| Description | Mouse monoclonal [SPM591] antibody to Basic Cytokeratin. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM591 |
| Conjugate | Unconjugated |
| Immunogen | Solubilized keratin extract from human stratum corneum. |
| Isotype | IgG1 |
| Molecular Weight | 67 kDa (CK1) / 58 kDa (CK5) / 56.5 kDa (CK10) / 50 kDa (CK14) |
| Target | Basic Cytokeratin |
| Specificity | This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. |
| Reactivity | Human, Mouse, Rat |
| Applications | FC, IF, IHC-P, WB |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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