| Product Name | Anti-Bcl2L2 Antibody [PCRP-BCL2L2-1A4] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [PCRP-BCL2L2-1A4] antibody to Bcl2L2. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PCRP-BCL2L2-1A4 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human Bcl2L2 protein. |
| Isotype | IgG2b |
| Molecular Weight | 22-30 kDa |
| Target | Bcl2L2 |
| Specificity | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. |
| Reactivity | Human |
| Applications | FC, IF, IP |
| Working Dilutions | IP: 1-2µg / 100-500µg proteins, Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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