| Product Name | Anti-beta 2 Defensin / BD-2 Antibody - BSA and Azide free |
|---|---|
| Description | Goat polyclonal antibody to beta 2 Defensin / BD-2. |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Defensin beta-2. |
| Isotype | IgG |
| Target | beta 2 Defensin / BD-2 |
| Specificity | This antibody recognises human Defensin beta-2 (BD-2), a ~4.3kDa cationic antimicrobial peptide, also known as Beta-defensin 4A or Skin-antimicrobial peptide 1 (SAP-1) expressed primarily by epithelial cells of the respiratory tract and skin, and an important component of the innate immune response against microbial infections.Expression of BD-2 is induced during inflammation in response to bacterial products and cytokines, and is initially expressed in a precursor form, which is cleaved to release the C-terminal active portion of the protein which is secreted by the neutrophil and binds to bacterial membranes causing their disruption. |
| Reactivity | Human |
| Applications | ELISA, FA, IHC-P, WB |
| Working Dilutions | ELISA: 0.5 - 2 µg/ml, Functional Assays: 5.0 - 8.0 µg/ml, WB: 0.1 - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 100 µg/ml after reconstitution. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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