| Product Name | Anti-beta NGF Antibody - BSA and Azide free |
|---|---|
| Description | Rabbit polyclonal antibody to beta NGF. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | E. coli derived recombinant human beta-NGF. |
| Isotype | IgG |
| Target | beta NGF |
| Specificity | This antibody recognises beta-Nerve Growth Factor (beta-NGF), a member of the neurotrophin family of proteins. Beta-NGF plays a crucial role in neuronal cell survival and differentiation. It is also critical for the development and maintenance of the nervous system. Beta-NGF elicits its biological function through the transmembrane recetprs trkA and p75NTR. Upon activation of these receptors by beta-NGF, a multitude of signaling pathways are stimulated including MAPK, PI3K and ERK, that sensitize neurons and stimulate growth of axons and dendrites. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Working Dilutions | ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 1 mg/ml after reconstitution. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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