| Product Name | Anti-BNP Antibody [NPPB/4493] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [NPPB/4493] antibody to BNP. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | NPPB/4493 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment corresponding to human BNP. The exact sequence is proprietary. |
| Isotype | IgG1 |
| Molecular Weight | 25-36 kDa (glycosylated BNP precursor) / 12 kDa (deglycosylated mature BNP) |
| Target | BNP |
| Specificity | Natriuretic peptides comprise a family of three structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP). ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. These peptides possess potent natriuretic, diuretic and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. ANP, BNP and CNP are highly homologous within the 17-residue ring structure formed by an intramolecular disulfide linkage. The genes which encode for ANP and BNP map to human chromosome 1p36.22. The gene which encodes for CNP maps to human chromosome 2q37.1. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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