| Product Name | Anti-BRG1 Antibody [BRG1/6531R] |
|---|---|
| Description | Recombinant rabbit monoclonal [BRG1/6531R] antibody to BRG1. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | BRG1/6531R |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment (around Amino Acids 200-400) of human SMARCA4 protein. The exact sequence is proprietary. |
| Isotype | IgG |
| Molecular Weight | 185 kDa |
| Target | BRG1 |
| Specificity | The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2) are the ATPase subunits of the mammalian SWI/SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI/SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/ SNF, including the NURF (nucleosome remodeling factor). |
| Reactivity | Human |
| Applications | ELISA, IHC-P, WB |
| Working Dilutions | WB: 1-2 µg/ml, IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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