Anti-C3a R Antibody [hC3aRZ1]

Category: Antibodies
Catalog
A280577
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Product Name Anti-C3a R Antibody [hC3aRZ1]
Description Mouse monoclonal [hC3aRZ1] antibody to C3a R.
Host Mouse
Clonality Monoclonal
Clone hC3aRZ1
Conjugate Unconjugated
Immunogen Recombinant human C3aR protein.
Isotype IgG1
Target C3a R
Specificity This antibody recognises the receptor for human complement component C3a (C3aR), a ~55 kDa cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors.
Reactivity Human
Applications IHC-Fr, FC
Working Dilutions Flow Cytometry: 1:10 - 1:20, Use 10µl of the sugested working dilution to label 1x106 cells in 100µl.
Form Liquid
Diluent Buffer Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Concentration 1 mg/ml
Storage Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
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